Current team

Current team

María Eugénia Vaquero Morales, PhD

María Eugénia Vaquero Morales, PhD

PhD researcher

I obtained a degree in Biology at the Complutense University of Madrid in 2009. After finishing my degree studies, I joined the group of Biotechnology for Lignocellulosic Biomass at the Centro de Investigaciones Biológicas (CIB-CSIC) with a contract co-financed by the company Abengoa Bioenergy with the aim to improve the production of fungal cellulases, key enzymes in the production of second generation bioethanol. After this period, I obtained a competitive PhD grant (FPU) from the Spanish Ministry of Education and Science to develop my PhD. My Thesis was focused on the heterologous expression of various fungal lipases, its characterization and the study of its possible biotechnological applications in several fields such as the synthesis of polymers and the production of nutraceuticals. I obtained my PhD in November 2015. During my training period, I made a 3-month stay at the Royal Institute of Technology (KTH) of Stockholm.

In May of 2017, I joined the Cajal Institute, where I am involved in several projects: although my work focuses mainly on the production of designer cellulosomes (self-assembled protein complexes that use some bacteria to degrade cellulose). I am also interested in other biological processes such as the functioning of the proteasome (protein degradation machinery) and the study of other proteins that can form amyloids.

email: mevaquero@cajal.csic.es

María del Carmen Fernández

María del Carmen Fernández

PhD Student

I obtained a degree in Biotechnology in 2009, and a Master in Management and Administration of Biotechnology Enterprises in 2010, both at Francisco de Vitoria University, Madrid. I carried out my Undergraduate Research Project during the summer of 2009 at the Albert Einstein College of Medicine in New York, focusing my work in the characterization of TORC1 pathway. Due to my interests in neuroscience and my desire to acquire more knowledge in this field, I started a Master in Neuroscience at the Autonomous University of Madrid, finishing in March 2012.  The Master thesis focused on the nanomechanics of tau protein.

I arrived to Dr. Mariano Carrión laboratory at the Instituto Cajal-CSIC in April 2011. My main objective at this moment was to do my Master Project and afterwards to star my PhD formation in the area of nanomechanics of neurotoxic proteins at single-molecule level. I am currently working in the study of functional and cytotoxic amyloidogenic proteins. This work try to shed some light on essential research questions as the amyloidogenic nature of specific neurotoxic proteins (Aβ and Tau) to eventually reveal the structural determinants of neural dysfunction in Alzheimer´s Disease.

email: mcarmen.fernandez@cajal.csic.es

 

 

Daniel Ramírez de Mingo

Daniel Ramírez de Mingo

PhD student

I obtained a degree in Biochemistry at the University of Zaragoza in 2013. During the last year of my degree, I collaborated with the the Apoptosis, Immunity and Cancer Research Group at the Faculty of Sciences of Zaragoza, where I tested the effect of derivative ruthenium compounds as a potential chemotherapeutic agents for negative breast cancer. The obtained results were published in The Journal of Medicinal Chemistry.

In 2013, I enrolled an Inter-University Master degree in Genetics and Cellular Biology at the Complutense University of Madrid, the Autonomous University of Madrid and the University of Alcalá de Henares. I did my Master Degree Thesis at the Biological Research Centre where I studied the role of Ring1B subunit of Polycomb Repressive Complex 1 during DNA replication.

In 2015 I joined the laboratory of Dr. Mariano Carrión at the Cajal with the aim to undertake my Doctoral Thesis. Currently, I am working on three lines of research: i) the evaluation of the effect of the antiamyloidogenic peptide QBP1 against functional CPEB3 amyloidogenesis and potential therapeutic applications; ii) the identification of differences between functional and pathological amyloids with CPEB3 protein as a model protein for amyloid research; iii) the determination of preferred conformations of CPEB3 protein by RMN and the effect of post-translational modifications that regulate its function.

Email: danielramirez@cajal.csic.es

Paula López García

Paula López García

PhD Student

I obtained a degree in Biochemistry by the Complutense University of Madrid in 2016, performing my Undergraduate Research Project in the Molecular Oncology Laboratory of the San Carlos Clinical Hospital about an "In vitro model of a mutation in GATA-1 ". Nowadays, I have just finished the Master in Neuroscience at the Autonomous University of Madrid (March 2018) and I have done my Master's Final Project on the "Effect of the anti-amyloidogenic peptide QBP1 on the CPEB-3 protein involved in memory consolidation: possible applications in the therapy of posttraumatic stress disorder".

I joined the laboratory of Dr. Mariano Carrión at the Cajal Institute in June 2017 with the aim of completing the Master's Thesis and continuing my training with the completion of a Doctoral Thesis. Currently I continue my work on the behavioral and phenotypic characterization of the transgenic mouse QBP1, an anti-amyloidogenic peptide, in order to determine the in vivo effect of this peptide in mammals and characterize the involvement of functional amyloid CPEB3 in memory consolidation.

Email: paula_bas11@hotmail.com

Emilio Tejera, PhD

Emilio Tejera, PhD

Laboratory technician

In addition to my work as lab technician, I have worked in some aspects of the laboratory research related to the function of cadherins in hearing system. Also, I temporarily worked as Provisional Project Manager for the CellulosomePlus European Project.

I obtained my Biochemistry degree by Autónomous University of Madrid (UAM) in 2006. My thesis (directors: M. Yáñez-Mo, Ph.D. and F. Sánchez-Madrid, Ph.D.) was developed about influence of tetrapanins on cellular adhesion and migration. Later, I carried out a postdoctoral stay in the laboratory of J. Reichenbach, M.D., Ph.D. (Zürich, Switzlerand) focused on Chronic Granulomatous Disease (CGD) patients. Nowadays, civil servant as lab technician in the Instituto Cajal-CSIC.

 

 

Elena Solera Segura, PhD

Project Manager

I obtained a degree in Biology at the University of León in 2006. This year I started my PhD at the Institute of Biotechnology of León (INBIOTEC). My Thesis research was focused in the characterization of the biosynthetic cluster of the immunosuppressant tacrolimus in two Streptomyces sp., obtaining my PhD in December 2014. This year, I finished my Bachelor Degree in Business Administration at the University of León.

In 2015, I  specialized in the detection, management, ideation and writing of proposals for the Horizon 2020 funding program through the realization of a professional Master at RTDI Innovation School, as well as in the administrative and technical management of these projects through an intensive workshop on management and leadership on European R&D&i projects. To complete my education on R&D management, in 2018 I obtained  the expert certificate on promotion and management of projects and international R&D&i activities at the Polytechnic University of Madrid promoted by the CDTI. 

In 2017, I joined the Protein Nanomechanics Laboratory at the Cajal Institute -CSIC (Madrid) as a project manager whEere I am responsible for the technical and economic management of several European and national projects, as well as for the ideation, writing and management of several proposals submitted to the H2020 Program, and other international and national calls.

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